Reversing
Hypertension: A Vital New Program to Prevent, Treat and Reduce High Blood
Pressure
by Julian M. Whitaker, M.D.
CHAPTER 1
Hypertension:
Action Alert
Hypertension affects an estimated 50
million Americans-more than one in three American adults. It is the lit
fuse of a bomb waiting to go off. Hypertension triples your risk of dying
from a heart attack and increases your risk of stroke sevenfold over
someone with normal blood pressure. Yet hypertension is largely
symptom-free-until it's too late. Hypertension is classified as a
cardiovascular disease (CVD), a disorder afflicting the heart or blood
vessels. According to 1999 American Heart Association (AHA) statistics,
58.8 million Americans suffer one or more of the cardiovascular diseases,
making CVD an epidemic of unbelievable proportions. CVD mortality rates
actually outrank our country's next seven leading causes of death combined
(including cancer). Every year 959,227 Americans die of CVD. That's 2,600
per day, or 1 every 33 seconds, which accounts for 41.4 percent of the
total deaths in the United States. Imagine, nearly half of all Americans
will die from cardiovascular disease-and hypertension is a primary
contributor to many of these deaths. If you don't take control of and
effectively manage your blood pressure, it will take control of you.
Although hypertension is extremely common,
it is painless and usually symptom-free. Hypertension does occasionally
give subtle warning signs. You might, for example, experience troublesome
headaches. These are usually located in the back of the head and upper
neck and are most acute in the morning, when blood pressure is relatively
low. Vision problems, dizziness, fatigue, abnormal sweating, insomnia,
shortness of breath, and excessive flushing of the face are other symptoms
you might experience. Any one or a combination of these might signal
hypertension. Although these symptoms could also stem from other
conditions, if you are experiencing any of them I urge you to consult your
physician immediately and have your blood pressure monitored.
Many people with hypertension are
completely unaware that they have this insidious condition: of the 50
million Americans with hypertension, only 68.4 percent are aware that
their blood pressure is high. This is why I recommend that everyone over
age 35 have their blood pressure checked regularly. Although hypertension
can strike at any age, blood pressure tends to increase steadily with age,
so regular checkups become even more important as you get older.
Measuring Blood Pressure
Having your blood pressure checked is quick
and painless. It is usually done with a stethoscope and a sphygmomanometer
(sphygmo means "pulse"), which consists of an inflatable arm
cuff attached to a column of mercury and a gauge (see Figure 1). Although
newer technologies in monitoring-including wrist and finger cuffs with
digital readouts-are becoming more and more popular for home and clinic
use, the sphygmomanometer remains the standard.
Here's how a sphygmomanometer works. The
cuff, which is wrapped around the upper arm just above the elbow, is
inflated with air to compress the brachial artery, the major artery in the
arm. The cuff is first inflated to a pressure that shuts off all of the
blood flow through the artery. As the cuff is slowly deflated, the person
taking the blood pressure reading listens through a stethoscope placed on
the brachial artery for the first audible beat-the sound of blood rushing
back into the compressed artery-and notes the number on the gauge. (A
computer chip in the electronic versions does this for you.) This
indicates the systolic blood pressure, or pressure generated by the heart
immediately after it contracts, or beats, and represents the top number of
the blood pressure reading.
As pressure from the cuff continues to be
released, the beats become stronger and more distinct, then taper off and
disappear. The number at which the last beat is audible indicates the
diastolic pressure, or the arterial pressure maintained between
heartbeats, when the heart is at rest. The combined ratio of systolic over
diastolic reveals the relative pressure generated by the heart as it
alternately pumps blood through the arteries and rests. The fraction is
expressed in millimeters of mercury (mm Hg), which refers to the amount of
mercury displaced by the arterial pressure during the reading. So a blood
pressure reading of 120/80 mm Hg represents a systolic pressure of 120 and
a diastolic pressure of 80. A blood pressure reading will indicate one of
three states: hypotension (low blood pressure), normotension (normal blood
pressure), or hypertension (high blood pressure). Normotension is, of
course, the ideal. In fact, it's one of the best predictors of a long
life. Low blood pressure may not be entirely desirable, but because it is
relatively rare, it will not be discussed in this book. If the reading
indicates hypertension, your health is in danger, and you need to take
immediate steps to bring your blood pressure down to healthier levels.
Making the Diagnosis
There is general agreement that optimal
blood pressure is 120/80 or less. However, exactly what blood pressure
constitutes hypertension is subject to some interpretation. In the past a
diagnosis of hypertension was often based exclusively on diastolic blood
pressure (the bottom number in the blood pressure reading). If your
diastolic pressure was over 90, you had high blood pressure. It was felt
that because the heart takes longer to rest than it does to beat, the
diastolic measurement was more significant. However, more recent research
has made it clear that an elevated diastolic pressure is no more hazardous
than a high systolic reading-and the latter appears to be an even more
accurate predictor of cardiovascular risk. The current consensus is that
elevations in either systolic or diastolic blood pressure readings should
be taken seriously. This is particularly true among older people, who may
have dangerously high systolic readings while maintaining virtually normal
diastolic blood pressure.
According to current American Heart
Association guidelines, hypertension is clinically defined as a systolic
blood pressure greater than 140 or a diastolic pressure greater than 90.
This echoes the recommendations of the Joint National Committee on the
Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC),
a widely respected National Institutes of Health task force of physicians
who are experts in hypertension and whose recommendations are approved by
most major organizations. The JNC, which updates its recommendations
periodically, published its sixth and latest report of guidelines in
November 1997. The committee devised an updated system of diagnosis using
both systolic and diastolic blood pressures to assess a patient's health
risk. The guidelines also recommend that clinicians specify other known
risk factors, including smoking, immoderate drinking, and routine
overeating. All of this information is then combined to determine the
stage of risk for a specific patient. The higher the stage, the greater
the patient's risk of a heart attack or stroke.
However, more recent research suggests that
blood pressure readings for a diagnosis of hypertension might need to be
adjusted downward. In June 1998, results of the Hypertension Optimal
Treatment (HOT) trial, a five-year study involving almost 19,000 patients
from 26 countries, were published in The Lancet, one of the world's
leading medical journals. Researchers found that patients who were able to
lower their systolic blood pressure to an average of 138.5 mm Hg and their
diastolic blood pressure to an average of 82.6 had major reductions in
heart attack and stroke risk. In early 1999, the World Health Organization
and the International Society of Hypertension recommended that the upper
limit for high normal blood pressure be lower, 130/85 (down from the JNC's
upper limit of 139/89). They based this on findings of the HOT trial and
other studies showing that stroke and heart attack risk are dramatically
reduced when diastolic blood pressure is less than 85.
You may be thinking, "Why quibble over
such small numbers? What's the difference between 85 and 89?"
According to an article published in the Journal of the American Medical
Association in March 1999, a decrease in diastolic blood pressure of only
5 to 6 points lowers your risk for stroke 42 percent.
So when should you be concerned about your
blood pressure? Since risk factors decrease as blood pressure goes down,
I'd have to agree with the most recent findings. If your blood pressure is
above 130/85, you should institute the measures outlined in this book for
reversing hypertension and aim to get into the optimal range of 120/80 or
lower.
Check and Recheck Your Blood Pressure
If you have high blood pressure based on a
blood pressure reading in your doctor's office, don't panic. Before a true
diagnosis is made you should return to the clinic on at least three
separate occasions (six return visits for monitoring are even better), so
your doctor can evaluate whether your blood pressure is consistently
elevated. Your blood pressure changes constantly throughout the day,
depending on your environment, activities, diet, emotions, medication, and
other factors. Even so simple a thing as talking can dramatically raise
your blood pressure. In a 1998 study carried out at the Clinique
Cardiologique in Paris, researchers measured the blood pressures of 50
patients with hypertension while they were actively talking, silently
reading, or sitting quietly. During the talking period blood pressure
significantly increased-by an average of 17 mm Hg systolic and 13 mm Hg
diastolic-and it remained elevated, although to a lesser degree, for a
time afterward. Silent reading actually lowered blood pressure more than
did merely sitting quietly.
Another cause of elevated blood pressure
readings-in the absence of true hypertension-is what is known as
"white-coat hypertension." For many people, visiting a doctor is
stressful, and the sheer anxiety of being examined by a health
professional temporarily elevates blood pressure. When this reaction
occurs, an inexperienced or hasty medical practitioner may misdiagnose the
patient as having hypertension solely on the basis of one or two in-office
blood pressure readings. White-coat hypertension is an all-too-common
phenomenon that can result in expensive, unnecessary, and potentially
hazardous treatment. Despite frequent and supposedly accurate measurements
of blood pressure, as many as 12 million patients in the United States may
be misclassified as hypertensive.
For this reason, I turn to a test called
the twenty-four-hour ambulatory blood pressure monitoring (ABPM) system.
This device measures blood pressure every fifteen to thirty minutes and
can help determine if a patient has true hypertension. The computerized
ABPM monitor is about the size of a paperback book and is attached to a
blood pressure cuff. The cuff is worn around the patient's arm, while the
monitor is worn on a belt around the waist or over the shoulder like a
purse. While the ABPM can take blood pressure readings over a
twenty-four-hour period, I have my patients wear it for just twelve to
eighteen hours, since I don't want to rob them of a night's sleep. This
still gives me the information I need for an accurate evaluation of their
blood pressure, allowing me to rule out white-coat hypertension and treat
only those patients with true hypertension. Unfortunately, the
overwhelming majority of patients are still being diagnosed with
hypertension based solely on a few readings taken in a doctor's office. I
feel this is a grave mistake. The authors of a 1993 Journal of the
American Medical Association study reported that as many as
"twenty-one percent of the patients diagnosed as having borderline
[high normal] hypertension in the clinic were found to have normal blood
pressure readings on ambulatory monitoring." And the sad part about
it is that many of these perfectly normal patients are needlessly placed
on prescription medications that might actually make them sick.
Guidelines for Having Your Blood
Pressure Taken
Here are a few things to consider when
having your blood pressure taken in your doctor's office to ensure the
most accurate readings.